Small intestinal ion transport

Small Intestinal Glucose Transport

Proximal and distal small intestinal segments of the rat were perfused in situ at two different rates with isotonic solutions containing glucose in concentrations ranging from 25 to 600 mg/100 ml. Absorption was measured as glucose disappearance rate from the lumen. Glucose absorption had not previously been studied at intraluminal concentrations above and below blood glucose. Absorption was mo...

Intestinal ion transport in NKCC1-deficient mice.

The Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) located on the basolateral membrane of intestinal epithelia has been postulated to be the major basolateral Cl(-) entry pathway. With targeted mutagenesis, mice deficient in the NKCC1 protein were generated. The basal short-circuit current did not differ between normal and NKCC1 -/- jejuna. In the -/- jejuna, the forskolin response (22 microA/cm(2); b...

Small Intestinal Lymphangioma Invagination

Nous presentons le cas d'un jeune homme de 25 ans qui s·est presente a notre service avec le symptomatologie de !'abdomen aigue. Les investiga­tions preoperatoire ne montrent pas J'etiologie de son etat.  A.laparotomie on trouve une tumeur polypeuse (Lymphangiome) de la muqueuse jejunale causant l'invagination et la necrose de la paroi intestinale. 

OSR1-sensitive small intestinal Na+ transport.

The oxidative stress responsive kinase 1 (OSR1) contributes to WNK (with no K)-dependent regulation of renal tubular salt transport, renal salt excretion, and blood pressure. Little is known, however, about a role of OSR1 in the regulation of intestinal salt transport. The present study thus explored whether OSR1 is expressed in intestinal tissue and whether small intestinal Na(+)/H(+) exchange...

Intestinal ion transport and the pathophysiology of diarrhea.